Output details
15 - General Engineering
University College London
Article title
A Poly(Lactic Acid-Co-Caprolactone)-Collagen Hybrid for Tissue Engineering Applications.
Type
D - Journal article
Title of journal
Tissue Engineering Part A: Tissue Engineering
Article number
-
Volume number
15
Issue number
7
First page of article
1667-
ISSN of journal
1937-3341
Year of publication
2009
URL
-
Number of additional authors
6
Additional information
Utilizing the properties of natural and synthetic scaffolding materials developed for Tissue engineering applications, we fabricated and tested in vivo a previously developed cell seeded hybrid construct consisting of a warp-knitted mesh of poly(lactic acid-cocaprolactone)(PLACL) coated with compacted type I collagen using a patented method. The construct was matured in vitro to develop a mature keratinocyte surface distribution like skin and tested in a lapine skin model. The results suggest that this could be used effectively in the initial stages of skin healing as a replacement for full thickness skin grafts.
Interdisciplinary
-
Cross-referral requested
-
Research group
None
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
