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Output details

15 - General Engineering

University of Warwick

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Output 1 of 344 in the submission

Article title

A coupled drug kinetics-cell cycle model to analyse the response of human cells to intervention by topotecan

Type

D - Journal article

DOI

10.1016/j.cmpb.2007.11.002

Title of journal

Computer Methods and Programs in Biomedicine

Article number

Volume number

Issue number

First page of article

169

ISSN of journal

0169-2607

Year of publication

2008

URL

Number of additional authors

Additional information

The work reported in this paper stemmed from research performed on the BBSRC funded grant proposal E19292 “The biology of drug targeting: Predictive mathematical modelling of drug impact in complex and dynamic cell populations”. It was an invited submission for a special edition of the journal following presentation at the 7th IFAC BMS Symposium, Aalborg, Denmark, August, 2009. The collaboration has also led to EU FP7 Marie Curie ITN EID funding for the project IMPACT (PITN-GA-2012-316736, £1.18M) in collaboration with AstraZeneca Sweden (Peter.Gennemark@astrazeneca.com) and NC3Rs /EPSRC (No. K001205/1, £307k) with AstraZeneca UK (contact james.yates@astrazeneca.com).

Interdisciplinary

Cross-referral requested

Research group

6 - Systems Modelling and Measurement

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract