Output details
15 - General Engineering
Swansea University
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Article title
Stroboscopic fluorescence lifetime imaging
Type
D - Journal article
Title of journal
Optics Express
Article number
-
Volume number
17
Issue number
7
First page of article
5205
ISSN of journal
1094-4087
Year of publication
2009
URL
-
Number of additional authors
6
Additional information
This paper presents the first demonstration of a wholly novel experimental technique for time resolved fluorescence imaging. There are two established approaches to temporal resolution, i. direct observation in time domain using fast detectors or ii. indirect observation from frequency response measurements. This paper presents an approach based on modulated pulsed excitation (stroboscopic) and d.c. detection. It transforms the measurement of fluorescence lifetime in that it uses time integrated detection thus avoiding the usual trade-off between high speed resolution and low detection signal. The work was funded by EPSRC grant, EP/E013104/1
Interdisciplinary
-
Cross-referral requested
-
Research group
A - Multidisciplinary Nanotechnology Centre
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-