Output details
15 - General Engineering
University of Southampton
A microfluidic device for the characterisation of embolisation with polyvinyl alcohol beads through biomimetic bifurcations
Significance of output:
Over 3 million scientific procedures using animals are carried out in the UK annually costing over £10 billion. There therefore is increasing demand for alternative methodologies for Reduction, Refinement and Replacement (3Rs) of animal models. We developed a biomimetic artificial vascular network model for quantitative characterisation of embolization (a therapeutic procedure using microparticles to block blood flow to tumours), by integrating multidisciplinary expertise from both academia and industry. The results have found applications in manufacturing embolic microparticles <Andrew.Lewis@biocompatibles.com> , leading to an industrial funded PhD project towards further insight understanding of the relevant clinical process and product design.
