Output details
12 - Aeronautical, Mechanical, Chemical and Manufacturing Engineering
University of Bath
Article title
A theoretical approach to zonation in a bioartificial liver
Type
D - Journal article
Title of journal
Biotechnology and Bioengineering
Article number
-
Volume number
109
Issue number
1
First page of article
234
ISSN of journal
0006-3592
Year of publication
2012
Number of additional authors
2
Additional information
The liver is a highly organised, structured organ that carries out many physiological functions. This paper is the only account of developing and modelling a bioartificial liver that considers the structure and oxygen gradients through the liver sinusoid compartments, i.e. the periportal, pericentral and perivenal zones. Previous reports only considered the average properties across the complete sinusoid, so this an original study that includes realistic liver physiology in the model. The paper arises from our previous work on modelling a bioartifiial liver (Davidson et al, 2011, Biotechnol Bioeng).
Interdisciplinary
-
Cross-referral requested
-
Research group
E - Biochemical and Biomedical Engineering
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
