Output details

Significant deterioration in nanomechanical quality occurs through incomplete extrafibrillar mineralization in rachitic bone: evidence from in-situ synchrotron X-ray scattering and backscattered electron imaging.

This paper is the first proof-of-concept that high brilliance synchrotron X-ray techniques can identify nanometre level fracture-critical alterations in metabolic bone disease at orders of magnitude (>1000) higher resolution than with current techniques. It led to a successful PhD studentship funding with Diamond Light Source and MRC-Harwell and collaboration with MCBR Sheffield and MRC Southampton for clinical translation. It led to ASMBR Young Investigator Travel Award and best Doctoral Thesis award at the European Society of Biomechanics 2013 and invited talks at MRS 2012 and ECOO 2012