Output details
15 - General Engineering
Queen Mary University of London
Tough lessons from bone: Extreme mechanical anisotropy at the mesoscale
This paper, funded by a Minerva Foundation grant to understand mechanisms of bone toughness, is the first to translate a small-scale microscopic laser-milling method used in high throughput cell sorting to an innovative method to understand the anisotropic mechanics of bone at mesoscopic length scales (10-100microns). We identified a key contributor to bone toughness to be weak interfaces between bone tissue packets (a few hundred microns wide), which can change strength and stiffness by over ~100 times. The research led to invited talks at ESF workshops, ACS PMSE Symposium, and collaboration with six internationally leading groups.