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Output details

15 - General Engineering

Imperial College London

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Output 103 of 109 in the submission
Article title

Tonic inhibition enhances fidelity of sensory information transmission in the cerebellar cortex.

Type
D - Journal article
Title of journal
Journal of Neuroscience
Article number
-
Volume number
32
Issue number
32
First page of article
11132
ISSN of journal
1529-2401
Year of publication
2012
URL
-
Number of additional authors
4
Additional information

This is one of only four studies ever to report electrical recordings in vivo from the smallest cells in the body: cerebellar granule cells. We developed this method and in the paper we use it to reveal mechanisms by which alcohol and neurosteroids disrupt cerebellar activity and thus motor coordination. The research was presented in invited lectures at Yale (2008) and National University of Singapore (2012) and sparked a new collaboration between Imperial and Prof G Augustine at Duke-NUS Medical School.

Interdisciplinary
Yes
Cross-referral requested
-
Research group
None
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-