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15 - General Engineering

King's College London

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Output 1 of 157 in the submission

Article title

[18F]2-fluoro-2-deoxy-D-glucose positron emission tomography (FDG PET) as a diagnostic tool for neurofibromatosis 1 (NF1) associated malignant peripheral nerve sheath tumours (MPNSTs) : a long-term clinical study

Type

D - Journal article

DOI

10.1093/annonc/mdm450

Title of journal

Annals of oncology : official journal of the European Society for Medical Oncology / ESMO

Article number

Volume number

Issue number

First page of article

390

ISSN of journal

1569-8041

Year of publication

2008

URL

Number of additional authors

Additional information

This highly cited paper (86 citations, Oct 13) evaluated FDG-PET/CT as a diagnostic tool for malignant peripheral nerve sheath tumours (MPNSTs) which are difficult to detect in neurofibromatosis (NF1) individuals. Dual time point imaging was introduced to improve diagnostic accuracy in this difficult group of paediatric and adult patients. The methodology developed in this publication is now used world-wide as part of the assessment of these patient groups. This research has led to MRC funding for further studies to optimise the PET scanning technique, reduce the patient radiation dose and develop more rapid scanning acquisitions.

Interdisciplinary

Cross-referral requested

Research group

None

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract