Output details
15 - General Engineering
University College London
Article title
Dynamic Filopodia Transmit Intermittent Delta-Notch Signaling to Drive Pattern Refinement during Lateral Inhibition
Type
D - Journal article
Title of journal
DEV CELL
Article number
-
Volume number
19
Issue number
1
First page of article
78
ISSN of journal
1534-5807
Year of publication
2010
URL
-
Number of additional authors
4
Additional information
This highly cited research builds a picture of how the dynamic behaviour of individual cells contributes to tissue form and function in normal development and cancer progression. It is shown that conventional models of signalling cannot account for the pattern formation in the fly notum. It challenges many pre-conceived notions in the field, and has therefore been widely cited for its importance and novelty (reviewed in Current Biology, Nature Reviews, Molecular Cell Biology, the Scientist, and Faculty of 1000). The work led to the award of BBSRC DTC King’s studentship to study the contact inhibition in developing embryos.
Interdisciplinary
-
Cross-referral requested
-
Research group
None
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
