Output details
15 - General Engineering
University College London
Enhancing the soft tissue seal around intraosseous transcutaneous amputation prostheses using silanized fibronectin titanium alloy
This study showed in vivo that hydroxyapatite with fibronectin and silanized fibronectin promotes a soft tissue seal around the intraosseous transcutaneous amputation prosthesis (ITAP). This is significant as achieving a tight seal around ITAP is necessary to prevent infection. ITAP improves the quality of life for amputees by avoiding many of the problems associated with socket prostheses such as poor fit, repeated fittings, recurrent skin infections, ulceration and pressure sores. This study is impacts on current clinical trials in the UK and US which utilised some of these coatings.