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Output details

15 - General Engineering

University College London

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Output 92 of 181 in the submission
Article title

Low-magnitude high-frequency mechanical signals accelerate and augment endochondral bone repair: preliminary evidence of efficacy.

Type
D - Journal article
Title of journal
J Orthop Res
Article number
-
Volume number
27
Issue number
7
First page of article
922
ISSN of journal
1554-527X
Year of publication
2009
Number of additional authors
2
Additional information

The potential for short duration (17 min), extremely low-magnitude (25 micrometer), high-frequency (30 Hz) interfragmentary displacements to enhance fracture healing was evaluated in a mid-diaphyseal, 3-mm osteotomy of the sheep tibia. These 25-micrometer displacements, induced by a ferroactive shape-memory alloy in the external fixator resulted in enhanced fracture healing. This application of low magnitude specific frequency stimulation in a translational large animal model provided evidence for the human clinical use of this in fracture healing.

Interdisciplinary
-
Cross-referral requested
-
Research group
None
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-