Output details

A general framework for experiment design in diffusion MRI and its application in measuring direct tissue-microstructure features.

<23>Theoretical underpinning of the emerging microstructure imaging paradigm. The paper introduces a powerful modelling and experiment design framework, including an active learning algorithm that optimizes imaging protocols over very high dimensional spaces to maximize sensitivity to specific biological parameters. Led to: major funding awards including my EPSRC Leadership Fellowship and the EU CONNECT consortium; invited talks, e.g. ISMRM diffusion workshop 2013 (500 participants); educational sessions, e.g. ISMRM 2011 (300 participants). Specific techniques built on the framework include ActiveAx axon diameter imaging (UCL), apparent exchange-rate imaging (Lund), quantitatve magnetization transfer (Surrey), NODDI (UCL), arterial spin labeling (Oxford).