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Output details

11 - Computer Science and Informatics

King's College London

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Output 44 of 159 in the submission

Article title

Derivative Scores from Site Accessibility and Ranking of miRNA Target Predictions

Type

D - Journal article

DOI

10.1504/IJBRA.2012.048966

Title of journal

International Journal of Bioinformatics Research and Applications

Article number

Volume number

Issue number

3-4

First page of article

171

ISSN of journal

1744-5485

Year of publication

2012

URL

Number of additional authors

Additional information

<17>The paper was presented at The Tenth Asia Pacific Bioinformatics Conference (APBC 2012) and forms an updated and extended version of the conference abstract. We propose scoring functions for the ranking of predicted miRNA targets. Our analysis of miRNA target predictions from PITA and STarMir against validated targets show that on average the ranking of validated targets was significantly improved based on our scoring functions in comparison to the rankings by PITA and STarMir. Our scoring functions result from a detailed analysis of the pareto front of the underlying multi-objective optimisation problem.

Interdisciplinary

Yes

Cross-referral requested

Research group

A - Algorithms and Bioinformatics

Citation count

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract