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13 - Electrical and Electronic Engineering, Metallurgy and Materials
University of Ulster
Raman spectroscopic monitoring of the osteogenic differentiation of human mesenchymal stem cells
The outcome of a collaborative project with Tyndall National Institute (Ireland) and funded under the Tyndall National Access and All-Ireland Functional Biomaterials R&D Programmes, this paper describes the first use of Raman as a non-invasive and enhanced alternative to standard FTIR in the study of bone differentiation and mineralisation and has demonstrated high spatial resolution cellular analysis. Using Raman along with biological and multivariate analysis we provide convincing evidence that Raman spectroscopy may be used to non-invasively study tissue formation and quality and provide a greater understanding of the tissue engineering process. Winner of best oral presentation, ESB 2011 (www.esbiomaterials.eu).
