Output details
15 - General Engineering
University of Edinburgh (joint submission with Heriot-Watt University)
Guided growth of neurons and glia using microfabricated patterns of parylene-C on a SiO2 background.
This paper reports the first guidance technology for cell growth that is compatible with normal CMOS chip fabrication. Guided cell growth is important for improved understanding of the behaviour of nerve cells, drug development and assay and, ultimately, prosthetics. This technique guides diverse cell types, including neurones, kidney cells and stem cells. This work was part of a collaboration with the Schools of Biomedical Sciences and Chemistry and led to follow-on project EP/E063322/1(£102k, 2008-11). It has been used by researchers world-wide, e.g. Cornell (DoI:10.3390/ma3031803); and the University of Tokyo (DoI:10.1002/btpr.739).