Output details
13 - Electrical and Electronic Engineering, Metallurgy and Materials
University of Sheffield : B - Materials Science and Engineering
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Output 0 of 0 in the submission
Article title
Dietary flavonoids inhibit the anticancer effects of the proteasome inhibitor bortezomib
Type
D - Journal article
Title of journal
Blood
Article number
-
Volume number
112
Issue number
9
First page of article
3835
ISSN of journal
15280020
Year of publication
2008
Number of additional authors
7
Additional information
This is the first ever study using Raman spectroscopy to monitor dietary flavonoids directly in human-plasma, specifically the detection of quercetin and myricetin. These are important as they inhibit the effectiveness of an anticancer drug, bortezomib, on leukaemia cells. This research has been employed by a number of clinical/non-clinical researchers (e.g., Ohio, Wayne, McGill Universities) internationally to identify inhibitor functions and drug manipulations of flavonoid activity.
Interdisciplinary
-
Cross-referral requested
-
Research group
None
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
