Output details
15 - General Engineering
University of Surrey
Article title
Characterisation of density distributions in roller-compacted ribbons using micro-indentation and X-ray micro-computed tomography
Type
D - Journal article
Title of journal
European Journal of Pharmaceutics and Biopharmaceutics
Article number
-
Volume number
72
Issue number
1
First page of article
173
ISSN of journal
09396411
Year of publication
2009
URL
-
Number of additional authors
-
Additional information
Roller compaction is one stage in a continuous pharmaceutical production operation, a relatively novel concept in the industry, to which the author has contributed in a number of papers analysing the compaction operation and the properties of the resulting compacts. In the present paper, it is demonstrated how conventional roller design leads to non-uniform feeding and therefore non-uniform compact properties. Continuous pharmaceutical production has advantages for product consistency, process footprint and cost and has been implemented by GlaxoSmithKline.
Interdisciplinary
-
Cross-referral requested
-
Research group
None
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
