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Output details

12 - Aeronautical, Mechanical, Chemical and Manufacturing Engineering

University of Sheffield : B - Chemical and Biological engineering

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Output 15 of 91 in the submission

Article title

Blade-granule bed stress in a cylindrical high shear granulator: I-Online measurement and characterisation

Type

D - Journal article

DOI

10.1016/j.ces.2012.04.019

Title of journal

Chemical Engineering Science

Article number

Volume number

Issue number

First page of article

ISSN of journal

00092509

Year of publication

2013

URL

Number of additional authors

Additional information

This paper highlights the development of a novel online telemetric impeller pressure sensor system in a high shear granulator (HSG) and mechanistic modelling of the blade-granule bed stress. A correction parameter was introduced to account for bed fluidisation. Knowledge of the stress is useful for studying granule growth kinetics and growth behaviour, ultimately to characterise granule properties. The model can be extended to HSGs of different designs and applied in HSG scale-up. Related awards: “Best Pharmaceutical Relevant Poster” at the 5th International Granulation Workshop by GlaxoSmithKline (2011), “Best Poster” at the 6th International Granulation Workshop by TTC (2013).

Interdisciplinary

Cross-referral requested

Research group

None

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract