Output details
12 - Aeronautical, Mechanical, Chemical and Manufacturing Engineering
University of Manchester : A - Chemical Engineering
Article title
Deep tunneling dominates the biologically important hydride transfer reaction from NADH to FMN in morphinone reductase
Type
D - Journal article
Title of journal
Journal of the American Chemical Society
Article number
-
Volume number
130
Issue number
22
First page of article
7092
ISSN of journal
0002-7863
Year of publication
2008
URL
-
Number of additional authors
3
Additional information
We showed previously (Science, 2006) that hydrogen transfer - an essential component of most biological reactions - is a quantum problem. The significance of this study (e.g. highlighted in JACS Select) is in identifying molecular motions that echo experimental observations – relating (macroscopic) kinetic observations to (microscopic) protein motions and dynamics. The work has underpinned subsequent studies by a range of academic-based groups.
Interdisciplinary
-
Cross-referral requested
-
Research group
None
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
