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Interactions between multiple sources of short-term plasticity during evoked and spontaneous activity at the rat calyx of Held

<28> A key aspect of this paper demonstrates the important contribution of background neural activity on the encoding of superimposed sound stimuli. The significance of this is recognised by citation in two review papers (A. Klug, Hearing Research 279:51-59, 2011; Deng & Klyachko, Communicative and Integrative Biology 4:543-548, 2011). This research has contributed towards a successful £351K BBSRC grant (led by Stirling and involving Edinburgh and Leicester) which started in November 2013. The aim of the grant is to explore the roles of short-term plasticity and ion channel modulation by Nitric Oxide in the constrained optimisation of neural performance.