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Output details

15 - General Engineering

University of Edinburgh (joint submission with Heriot-Watt University)

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Output 40 of 305 in the submission

Article title

Anisotropic fibrous scaffolds for articular cartilage regeneration

Type

D - Journal article

DOI

10.1089/ten.TEA.2011.0606

Title of journal

Tissue Engineering, Part A

Article number

Volume number

Issue number

19-20

First page of article

2073

ISSN of journal

1937-3341

Year of publication

2012

URL

Number of additional authors

Additional information

The paper reports the development of the first tri-layer electrospun scaffold that mimics the mechanical properties of cartilage in compression and tension and is able to incorporate living chondrocyte cells. This novel scaffold design was part of a patent filing (WO2012/080706 A2).This paper motivated follow-on work at Imperial College (DoI:10.1089/ten.tea.2012.0580 and DoI:10.1089/ten.tec.2013.0225) and is featured in two recent reviews (DoI:10.1089/ten.TEB.2012.0723.) and (Eur Cell Mater. 2013 May 2; 25:248-67). The work was funded by Wellcome Trust and EPSRC Osteoarthritis Centre of Excellence (£10.9M).

Interdisciplinary

Yes

Cross-referral requested

Research group

A - Manufacturing & Materials

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract