Output details
13 - Electrical and Electronic Engineering, Metallurgy and Materials
Sheffield Hallam University
Article title
Detection of beta-amyloid peptide (1-16) and amyloid precursor protein (APP770) using spectroscopic ellipsometry and QCM techniques: A step forward towards Alzheimers disease diagnostics
Type
D - Journal article
Title of journal
Biosensors and Bioelectronics
Article number
-
Volume number
26
Issue number
4
First page of article
1332
ISSN of journal
0956-5663
Year of publication
2010
Number of additional authors
5
Additional information
This collaborative work with Cranfield University, funded by the Ministry of Higher Education, Malaysia (MoHE), reports for the first time, the use of spectroscopic ellipsometry for the detection of bA-16 and APP770 in sub-ppb level in the presence, at a high background level, of other proteins. These molecules are key markers in the early diagnosis of Alzheimer's disease and this approach therefore has significant potential to be used as a fast and simple immunoassay for these bio-markers.
Interdisciplinary
Yes
Cross-referral requested
5 - Biological Sciences
Research group
None
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
