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Shear and extensional rheology of hydroxypropyl cellulose melt using capillary rheometry

Polymers are increasingly being used in pharmaceutical applications. This paper describes collaboration between Bradford and the Poona College of Pharmacy in India in which the flow behaviour of one such polymer (HPMC) was studied using capillary rheometry. This study was the first reported attempt to characterise the rheology of pharmaceutical polymers under conditions representative of manufacturing processes. Understanding these flow characteristics is a vital pre-formulation tool for development of new pharmaceutical processes such as melt extrusion. This work demonstrated the application of Dr Kelly’s expertise in rheology in a field outside that of the conventional plastics industry.