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12 - Aeronautical, Mechanical, Chemical and Manufacturing Engineering

University of Bradford

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Article title

Cocrystalization and Simultaneous Agglomeration Using Hot Melt Extrusion

Type

D - Journal article

DOI

10.1007/s11095-010-0273-9

Title of journal

Pharmaceutical Research

Article number

Volume number

Issue number

First page of article

2725

ISSN of journal

1573-904X

Year of publication

2010

URL

Number of additional authors

Additional information

Cocrystals are highly attractive to the pharmaceutical industry but limitations in production techniques have limited their uptake. A new continuous process based upon twin screw extrusion was developed at Bradford by an interdisciplinary research group formed by Dr Kelly (process engineering) and Professor Paradkar (pharmaceutical science). The initial research was supported through a Yorkshire Innovation fund, which employed a PDRA (Dr Dhumal). This project led to a patent application surrounding the technology being filed by the inventors (GB0813709.3), the award of a 3 year £495k EPSRC project (EP/J003360/1) and a recent synchrotron ESRF beam line award in Grenoble.

Interdisciplinary

Cross-referral requested

Research group

A - Advanced Materials Engineering

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract