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Scalable reactor design for pharmaceuticals and fine chemicals production. 3. A novel gas-liquid reactor for catalytic asymmetric transfer hydrogenation with simultaneous acetone stripping

Production of fine chemicals has various pitfalls which can result in worse performance when the scale is increased from lab to manufacture. This paper is the 3rd paper in a series on reactor design avoiding such pitfalls. The first 2 papers identified obstacles in scalability and provided a systematic approach of how to address them. In this paper this methodology resulted to a novel reactor design which is not only in principle easier to scale-up but also shows improved performance (lower reaction time) than the conventional batch reactor. Thus, the approach proposed provides a framework for better, faster reactor design.