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An accurate, fast and robust method to construct patient-specific cubic Hermite meshes

This study outlines a unique methodology to automatically build specialised mechanical cardiac meshes from clinical images. This work has changed the way engineering models are being applied to patient data for groups in Auckland, London and San Diego. Specific applications include enabling the characterization of diastolic heart failure [Xi, Medical Image Analysis, 2013] the use of personalised computational meshes as biomarker to characterise ventricular shape [Lewandowski, Circulation, 2013] and multiple animal models [Land, Biophys J, 2013]. The technique also underpins central work in a major on-going European project (VPH-Share). It is published in the leading medical imaging journal.