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Output details

15 - General Engineering

Queen Mary University of London

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Output 32 of 81 in the submission

Article title

Extracellular-matrix tethering regulates stem-cell fate.

Type

D - Journal article

DOI

10.1038/nmat3339

Title of journal

Nat Mater

Article number

Volume number

Issue number

First page of article

642

ISSN of journal

1476-1122

Year of publication

2012

URL

Number of additional authors

Additional information

The study provides an important paradigm shift in field of mechano-transduction: stem cells feel nano-scale properties rather than bulk properties. The work has been highlighted in high impact journals by other experts (Nat. Mater. News and Views 2012, v11; Science Editors’ choice, 2012, v336). The study helped secure further funding (Case studentship, £92k; EPSRC, EP/J501360/1, £21k; Royal Soc. Research Grant, £15k). The paper also led to invitation to two international conferences (Nanoscience 2013. China; ICFPAM13, New-Zealand) and to collaboration with groups of Prof. Duncan Sutherland (Aarhus University, Denmark, article in preparation) and Dr. Armando del Rio (Imperial College, London).

Interdisciplinary

Cross-referral requested

Research group

None

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract