Output details
15 - General Engineering
Queen Mary University of London
Article title
Controlled Intracellular Release of Peptides from Microcapsules Enhances Antigen Presentation on MHC Class I Molecules
Type
D - Journal article
Title of journal
SMALL
Article number
-
Volume number
5
Issue number
19
First page of article
2168
ISSN of journal
1613-6810
Year of publication
2009
URL
-
Number of additional authors
9
Additional information
The papers demonstrated the applicability of the concept of light stimulated release for intracellular operations. Oligopeptide was delivered to cells inside capsules and produced no effect unless its release was stimulated by laser shot. Release of oligopeptides caused intracellular reaction resulted on antigen presentation on cell membrane. This was for first time the proof of light stimulating while the substances is already in the cells and separation of uptake and intracellular trafficking. The paper was highlighted in MIT Technology news and TV media (France 24).
Interdisciplinary
-
Cross-referral requested
-
Research group
None
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
