Output details
13 - Electrical and Electronic Engineering, Metallurgy and Materials
University of Sheffield : B - Materials Science and Engineering
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Output 0 of 0 in the submission
Article title
Integrated culture and purification of rat Schwann cells from freshly isolated adult tissue
Type
D - Journal article
Title of journal
Nature Protocols
Article number
-
Volume number
7
Issue number
11
First page of article
1996
ISSN of journal
17502799
Year of publication
2012
Number of additional authors
2
Additional information
A breakthrough in culturing Schwann cells from adult nerve is reported, potentially transforming regenerative therapies requiring Schwann cells (e.g. nerve injuries). Traditionally, Schwann cell culture has been difficult, needing to isolate cells from neonates or embryos, typically resulting in low yield. We have identified a selective growth medium, unique to an enzyme expressed by Schwann cells. Consequently, Schwann cell culture is now easy, with a simple tissue digest and single growth step. Potential impacts will transform how neuroscience groups worldwide study Schwann cells for experimental and therapeutic use.
Interdisciplinary
-
Cross-referral requested
-
Research group
None
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
