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Output details

15 - General Engineering

University of Southampton

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Output 257 of 706 in the submission

Article title

Evaluation of a new high power, wide separation laser Doppler probe: potential measurement of deeper tissue blood flow

Type

D - Journal article

DOI

10.1016/j.mvr.2009.05.003

Title of journal

Microvascular Research

Article number

Volume number

Issue number

First page of article

155

ISSN of journal

0026-2862

Year of publication

2009

URL

http://www.ncbi.nlm.nih.gov/sites/entrez/19460391

Number of additional authors

Additional information

Significance of output:

There is an unmet need to make simple non-invasive measurements of biomarkers in tissues key to the pathogenesis of cardiovascular disease, e.g. muscle and adipose tissue. Laser Doppler fluximetry (LDF) had previously only been used to examine blood flow and response to stimuli in superficial (dermal) tissue. Theoretical, simulation and human studies are used to assess the capabilities of a high power device capable of measuring larger tissue volumes in-vivo in deeper tissue than before. Techniques for wavelet analysis of LDF signals developed in this study are now provided with software distributed by the manufacturer (contact gush@moor.co.uk, http://gb.moor.co.uk/product/moorvms-ldf1-hp-high-power-ldf/5).

Interdisciplinary

Cross-referral requested

Research group

None

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract