Output details

Structural analysis of alpha-helical proteins from wool using cysteine labelling and mass spectrometry

The wool fibre is complex with many distinct structural features which are composed of different proteins and associated reactivities. One of the most important constituent amino acids in the fibre is cysteine with its ability to influence fibre processing and performance. This paper demonstrates through the differential labelling of cysteine residues their relative accessibility within the native wool fibre and has developed a functionality map of chemical accessibility. Thus for the first time, the potential for targeting specific fibre regions and engineering fibre/fabric physical performance has been explored through this EU funded project.