Output details
15 - General Engineering
University of Hull
Hydroxyapatite nanoparticles: electrospinning and calcination of hydroxyapatite/polyvinyl butyral nanofibers and growth kinetics
This paper describes a novel process to prepare hydroxyapatite (HA) nanoparticles for bone substitute materials by electrospinning and calcination. Currently, HA is produced commercially in the form of micron-sized powders, which are typically 20 times larger than HA in normal bone matrix and exhibit poor bioresorbability and brittle characteristics. The new technique produces a highly pure, single phase nano-HA of a more compatible size to that found in bone, and has improved biomineralization characteristics in vitro with the promise of better biocompatibility and bioactivity in vivo.