Output details
12 - Aeronautical, Mechanical, Chemical and Manufacturing Engineering
University of Leeds
De novo designed positively charged tape-forming peptides: self-assembly and gelation in physiological solutions and their evaluation as 3D matrices for cell growth
Paper presents outcome of collaboration between Engineering (Wilcox), Chemistry (Aggeli) and Biology (Ingham) including work of PhD student Miles funded through EP/F010575/1 (Wilcox). Study focuses on fundamental characterisation and biocompatibility testing of novel self-assembling peptides developed at Leeds and demonstrates that they can be optimised for biomedical applications. Miles awarded PhD student of the Year from 2000 students across university for her research. Outcomes recognised at international conferences (podiums European Biomaterials Madrid 2013, TERMIS World Congress Vienna 2012), led to patent application (GB1306338.3) and follow-on funding (£1M ERC306615 and £3M Oxford collaboration EP/K020757/K021729/1; Wilcox) to develop peptides for spinal treatments.
