Output details

The dimensions and composition of stereociliary rootlets in mammalian cochlear hair cells: comparison between high- and low-frequency cells and evidence for a connection to the lateral membrane.

This study investigated tip-link proteins in hair cells, in mouse mutations providing strong evidence that the current model of transduction in hearing is correct in many of its details. It added to knowledge of hearing disorders like Usher syndrome, where tip-link proteins are affected, which may lead to therapies for such disorders. It was followed by an invitation to submit an up-to-date review to the Journal of Cell Science (2013, 126, 1721-31) on tip links and to revise the inner ear section of Gray’s anatomy for the 41st edition which is due to be published in 2014.