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An electrically-activated dynamic tissue-equivalent phantom for assessment of diffuse optical imaging systems

This describes the first tissue-equivalent optical phantom for simulating blood volume changes associated with cerebral haemodynamic activity, without the inconvenience of liquids or moving parts. The design employs pigments whose absorption is varied reversibly by localized electrical heating. This work has made it possible to exchange dynamic phantoms between research groups without the necessity to transport or prepare fluids. Such exchange has enabled groups in several European countries to compare performance and calibrate their imaging systems against a common reference for the first time. Our start-up company is assessing commercialization potential. I designed the phantom and am head of group.