Output details
15 - General Engineering
University of Oxford
Article title
Coating of adenovirus type 5 with polymers containing quaternary amines prevents binding to blood components
Type
D - Journal article
Title of journal
Journal of Controlled Release
Article number
-
Volume number
135
Issue number
2
First page of article
152
ISSN of journal
0168-3659
Year of publication
2009
URL
-
Number of additional authors
6
Additional information
The design and engineering of a novel polymer to improve biocompatibility of the anti-cancer agent adenovirus is described in this leading drug delivery journal. The technology now underpins patent US 2011/0243939A1 being exploited by Oxford University SME spin out PsiOxus Therapeutics Ltd (http://www.psioxus.com/). The work was supported by an interdisciplinary EU FP6 (LSHB-CT-2004-512087) that included collaborators from the Czech Republic, Germany, Holland and Sweden. Selected for oral presentation at two major gene and cell therapy conferences (Edinburgh, 2008) and Gene Delivery Symposium (Cold Spring Harbour, USA 2008).
Interdisciplinary
-
Cross-referral requested
-
Research group
E - Biomedical Engineering
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
