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13 - Electrical and Electronic Engineering, Metallurgy and Materials

University of Southampton

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Article title

Thin film polycrystalline silicon nanowire biosensors

Type

D - Journal article

DOI

10.1021/nl2042276

Title of journal

Nano Letters

Article number

Volume number

Issue number

First page of article

1868

ISSN of journal

1530-6984

Year of publication

2012

URL

http://www.eprints.soton.ac.uk/336302

Number of additional authors

Additional information

Significance of output:

This is the first paper to obtain antibody-antigen titration curves and quantitative values of binding constant from measurements on silicon nanowire FET biosensors. The biosensors were produced using a manufacturable top-down technology and commercialisation is being pursued through a TSB project (16520-124156 & EP/K502327/1, £2.3M) with Sharp Laboratories Europe (sally.anderson@sharp.co.uk) Oxford Instruments Plasma Technology and Aptamer Solutions. Nanowires were characterised in air and at each biofunctionalisation step and binding constants were compared with standard protocols. The research was funded by EPSRC (EP/6061696/1, £1.3M).

Interdisciplinary

Cross-referral requested

Research group

None

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract