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Magnetic resonance imaging of the newborn brain : manual segmentation of labelled atlases in term-born and preterm infants

Automatic labelling by propagation of segmentations from authoritative adult brain atlases to unseen target brains is highly effective from 2 year olds upwards [Gousias, Neuroimage, 2008]. Newborn brains have very different structures, which frustrate these approaches for this critically important stage in brain development. Here we created an entirely new database of atlases containing 50 manually outlined regions in 20 newborns. In a follow-up paper [Gousias, PLoS ONE, 2013] we demonstrated automatic labelling using these manual priors, paving the way for large scale developmental studies such as the ERC funded developing Human Connectome project (www.developingconnectome.org).