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15 - General Engineering
King's College London
Detection of Intracoronary Thrombus by Magnetic Resonance Imaging in Patients With Acute Myocardial Infarction
This is the first in-vivo demonstration of hyperintense coronary plaque (HIP) from thrombus using non-contrast enhanced T1 weighted (T1w) MRI in patients with acute coronary syndrome. This study builds on previous work form our group first describing the technique [Maintz EHJ 2006] and demonstrating HIP signature from haemorrhage [Oei Eur Radiol 2010]. A recent clinical study (550 patients) using our technique [Noguchi JACC 2013] demonstrated that patients with HIP (thrombus or haemorrhage) have a 25.8% coronary event rate compared to 1.1% in patients without HIP during a 55-month follow up period.