Output details
15 - General Engineering
University College London
A Poly(Lactic Acid-Co-Caprolactone)-Collagen Hybrid for Tissue Engineering Applications.
Utilizing the properties of natural and synthetic scaffolding materials developed for Tissue engineering applications, we fabricated and tested in vivo a previously developed cell seeded hybrid construct consisting of a warp-knitted mesh of poly(lactic acid-cocaprolactone)(PLACL) coated with compacted type I collagen using a patented method. The construct was matured in vitro to develop a mature keratinocyte surface distribution like skin and tested in a lapine skin model. The results suggest that this could be used effectively in the initial stages of skin healing as a replacement for full thickness skin grafts.