Output details
13 - Electrical and Electronic Engineering, Metallurgy and Materials
Imperial College London : B - Metallurgy and Materials
The role of intracellular calcium phosphate in osteoblast-mediated bone apatite formation.
The process of bone formation remains unexplained due to the technical challenge with acquiring spatially resolved chemical maps of this tissue in its native state. The paper provides a new fundamental understanding of the role that osteoblast cells play in forming bone. These insights have important implications for understanding aetiology of pathological mineralisation processes, such as the formation atherosclerotic plaques, which can be used to guide treatment of pathological mineralization and bone disease. This paper led to a plenary talk for the Materials Today, Frontiers of Microscopy conference and a keynote talk at the Irish Microscopy Society meeting, 2012.
