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Output details

13 - Electrical and Electronic Engineering, Metallurgy and Materials

Newcastle University

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Output 66 of 114 in the submission

Article title

Multi-site optical excitation using ChR2 and micro-LED array

Type

D - Journal article

DOI

10.1088/1741-2560/7/1/016004

Title of journal

Journal of Neural Engineering

Article number

016004

Volume number

Issue number

First page of article

ISSN of journal

1741-2552

Year of publication

2010

URL

http://dx.doi.org/10.1088/1741-2560/7/1/016004

Number of additional authors

Additional information

Optogenetics is a gene therapy method to photosensitize nerve cells and has revolutionary potential for the field of neuroprosthetics but requires an intense light stimulus. This paper is the first to demonstrate a device which could both stimulate large numbers of such neurons and translate to implantation. The key outcome of EPSRC project: EP/F029241, it directly contributed to the award of a €2.1M FP7 project (www.optoneuro.eu, PI-Degenaar), and a £13.9M (FEC) EPSRC/Wellcome award (Awaiting code –epilepsy prosthesis). The work is highlighted by the journal in its top ten most influential papers (http://iopscience.iop.org/1741-2552/page/Most%20cited%20papers), and has supported public engagement activity (e.g. http://www.theguardian.com/science/video/2011/apr/21/song-machine-human-plus-video)

Interdisciplinary

Cross-referral requested

Research group

C - Microsystems

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract