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Methods for predicting cortical UP and DOWN states from the phase of deep layer local field potentials.

This was the first paper to show how purely extracellular signals can be used to detect UP/DOWN state transitions – previously it had been assumed that it was necessary to use the whole-cell patch clamp technique. This paper was featured in Faculty of 1000 Biology (http://f1000.com/prime/3184978) and in the book “Cells – Advances in Research and Applications: 2012 edition” (A Ashton, ed). Our method has found its way into neurophysiological practice already (e.g. Hawking et al J Neurophys 2013;15:315-320) and also underlies subsequent methodological development (e.g. MacFarland et al PLoS ONE 2011;6: e21606).