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13 - Electrical and Electronic Engineering, Metallurgy and Materials

University of Leeds

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Output 51 of 64 in the submission

Article title

Surface-Immobilized Peptide Aptamers as Probe Molecules for Protein Detection

Type

D - Journal article

DOI

10.1021/ac701688q

Title of journal

Analytical Chemistry

Article number

Volume number

Issue number

First page of article

978

ISSN of journal

0003-2700

Year of publication

2008

URL

Number of additional authors

Additional information

CPW-2: This paper reports the oriented integration of robust antibody-mimetic engineered proteins into electronic devices, demonstrating that their biological activity, specificity, and selectivity against target biomarkers is maintained. With CPW-1, this underpins development of label-free clinical diagnostic technology, and contributed to the £11M Wellcome/EPSRC programme ('WELMEC' WT088908/Z/09/Z, PI:Fisher) and the ‘Regenerative Therapies and Devices’ IKC (EP/G032483, PI:Fisher, £4,886,149). It also led to a £497k STFC award (TP/05/07), two BBSRC CASE awards (with Abbott and Hitachi), funded collaborations with P&G (£35k) and Abbott (£80k), and supported our EPSRC CDT in molecular-scale engineering (EP/J500124, PI:Davies, £1,999,639; 30 PhD studentships with Sheffield).

Interdisciplinary

Yes

Cross-referral requested

Research group

None

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract