Output details
12 - Aeronautical, Mechanical, Chemical and Manufacturing Engineering
University of Manchester : A - Chemical Engineering
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Article title
Enzymatic Catalyzed Synthesis and Triggered Gelation of Ionic Peptides
Type
D - Journal article
Title of journal
Langmuir
Article number
-
Volume number
26
Issue number
13
First page of article
11297
ISSN of journal
1520-5827
Year of publication
2010
URL
-
Number of additional authors
6
Additional information
Author publishes as Miller (maiden name). A novel route for synthesising self-assembling ionic-complementary peptides is presented; start with a solution containing soluble, easy to synthesize peptides, and simply add an enzyme to couple the precursor peptides together. This resulted in a sol-gel transition which made it possible to trigger gelation in the presence of cells, hence forming a 3D scaffold ready for tissue engineering applications. This method enables synthesis of ionic peptides without harsh chemicals and water as the only by-product. Moreover the materials are being trialled by clinicians for cardiac repair through an EU project.
Interdisciplinary
-
Cross-referral requested
-
Research group
None
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
