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Output details

15 - General Engineering

Brunel University London

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Output 141 of 258 in the submission

Article title

Intermittent counter-current extraction as an alternative approach to purification of Chinese herbal medicine

Type

D - Journal article

DOI

10.1016/j.chroma.2008.12.005

Title of journal

Journal of Chromatography A

Article number

Volume number

1216

Issue number

First page of article

4187

ISSN of journal

00219673

Year of publication

2008

URL

http://www.sciencedirect.com/science/article/pii/S0021967308021341/pdfft?md5=41a63819205ba67ac908ef42aafe0cbd&pid=1-s2.0-S0021967308021341-main.pdf

Number of additional authors

Additional information

This paper demonstrated a small footprint preparative scale counter-current instrument has capability to operate with a throughput of up to 1 kg/day in a continuous mode in a large scale applications laboratory without needing expensive explosion proof hazard lab facilities. This was one of the key outputs of the TSB High value manufacturing research programme on “Scalable Technology for the Extraction of Pharmaceuticals” Grant No. TP14/HVM/6/I/BD506K. It demonstrated for the first time the importance of flying lead length and will be a key paper as continuous processing in CCC grows.

Interdisciplinary

Cross-referral requested

Research group

None

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract