Output details
12 - Aeronautical, Mechanical, Chemical and Manufacturing Engineering
University of Sheffield : A - Mechanical engineering and Advanced manufacturing
Are spontaneous fractures possible? An example of clinical application for personalised, multiscale neuro-musculo-skeletal modelling
This work falsifies, using stochastic multiscale modelling techniques, the clinical theory that spontaneous bone fractures are physically and physiologically impossible. The paper proves that spontaneous hip fractures are possible in patients with severe osteoporosis and significant neuromuscular degradation. The work generated significant interest in the clinical community, because it provides a possible explanation, using a probabilistic modelling framework, to those 5% of hip fractures that cannot be associated to any traumatic event. This paper was invited in association to the opening plenary lecture that Prof. Viceconti gave to the XXIII Congress of the International Society of Biomechanics in 2011.
