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Application of quantum dot barcodes prepared using biological self-assembly to multiplexed immunoassays

This work describes the application of quantum dot barcodes prepared by layer-by-layer biological self-assembly on magnetic beads to qualitative multiplexed immuno-assays. The methodology developed was highlighted in a review on Quantum Dot-Based Nano-composites for Biomedical Applications (Curr. Med. Chem. 18, pp3516-3528, 2011). It also underpinned Sakandar Rauf's successful University of Queensland Research Fellowship proposal. The ideas developed using magnetic separation in multiplexed immuno-assays resulted in two new collaborations: firstly, with Kaiam (Dr Mike Jubber, m.jubber@kaiamcorp.com) to develop arrayed waveguide grating micro-spectrometer based bio-sensing systems, and secondly, with Nissan Chemical, Japan (Dr Hitoshi, furusyouh@nissanchem.co.jp) on developing Lab-on-a-chip point-of-care devices.