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Magnetic Conjugated Polymer Nanoparticles as Bimodal Imaging Agents

This work, already cited 66 times (Oct 13), describes the synthesis of luminescent conjugated polymer nanoparticles that incorporate magnetic particles, capped with a lipid, allowing the potential attachment of biomolecules that allow targeted imaging. It also describes their use as dual modality imaging agents for tracking cells, at the microscopic level by optical imaging and at whole body level by MRI. Importantly these materials do not contain toxic heavy metals (as used for example in quantum dots) usually required for these applications. This opens up many potential applications in biomedical imaging and the material has been patented.